HESPERIDIN HYDROGEL FORMULATION USING PECTIN-CHITOSAN POLYMER COMBINATION

Chitosan Hydrogel Structure Modulated by Metal Ions

As one of the most important polysaccharide, chitosan (CS) has generated a great deal of interest for its desirable properties and wide applications. In the utilization of CS materials, hydrogel is a major and vital branch. CS has the ability to coordinate with many metal ions by a chelation mechanism. While most researchers focused on the applications of complexes between CS and metal ions, th...

About the Sterilization of Chitosan Hydrogel Nanoparticles

In the last years, nanostructured biomaterials have raised a great interest as platforms for delivery of drugs, genes, imaging agents and for tissue engineering applications. In particular, hydrogel nanoparticles (HNP) associate the distinctive features of hydrogels (high water uptake capacity, biocompatibility) with the advantages of being possible to tailor its physicochemical properties at n...

State of Water in Chitosan–PVA Hydrogel

The bound water fraction (XBW) of a newlydeveloped pH-sensitive, biodegradable chitosan-polyvinyl alcohol (PVA) hydrogel crosslinked with glutaraldehyde (GA) was investigated as a function of the chitosan/PVA molar ratio, GA concentration (CGA), and ionization state. Differential scanning calorimetry (DSC) was used to determine the XBW of the initial hydrogel, and of the hydrogel equilibrated i...

Polymer chemistry and hydrogel systems

Formulation and evaluation of effervescent floating tablet of famotidine with natural polymer chitosan

A Novel floating controlled release drug delivery system of famotidine was formulated in an effort to increase the gastric retention time of the dosage form and to control drug release. The present work investigates the approach using two different polymers HPMC K100 M and natural polymer Chitosan . A floating drug delivery system (FDDS) was developed using gas-forming agents, like sodium bicar...